Neurodegenerative disorders are categorized by progressive loss of neurons in different reason of the brain and cause various neuropsychiatric diseases including Stroke, Parkinson’s disease, tardive dyskinesia, epilepsy, Alzheimer’s disease, depression, psychosis, Obsessive compulsive disorder, anxiety and cerebrovascular impairment. Thus, many neuroprotective agents are being discovered to prevent further worsening of cell loss by acting on the function of receptors and other involved mechanisms. Synthetic neuroprotective agents have some unwanted side effects like drowsiness, dry mouth, sleepiness etc. Herbal medicines are in great demand because of their protective mechanisms with negligible side effects. Hence, there has been extreme interest focussed on herbals against neurodegeneration. Several plants parts such as flowers, fruits, leaves, stems, roots and seeds contains variety of phytoconstituents including alkaloids, flavonoids, steroids, phenolics, terpenoids, saponins etc studied pre-clinically (in-vivo and in-vitro) and clinically in various neurodegenerative diseases. This paper highlights the research reports on phytochemicals with neuroprotective potential.
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